O Regimento dos preços dos medicamentos... na farmácia brasileira oitocentista / Regulation of drug prices in nineteenth-century Bazilian pharmacy

Resumo Em 5 de novembro de 1808, dom João de Bragança promulgou um alvará sobre o exercício dos boticários e o preço das drogas e ordenou a criação de um regulamento para taxar o custo dos medicamentos comercializados no Brasil. Publicado pela primeira vez em 1809, o Regimento dos preços dos medicamentos... ganhou novas edições nos anos subsequentes e tornou-se um indispensável instrumento de trabalho para os envolvidos com a feitura e o comércio dos remédios. Este texto situa historicamente e destaca esse documento brevemente explorado pelos pesquisadores da história da farmácia brasileira, visto ter sido uma das primeiras iniciativas do governo luso-brasileiro condizentes com a atividade farmacêutica no Brasil no século XIX.

Abstract On November 5th, 1808, D. João de Bragança issued a license about the practice of druggists and the price of drugs and ordered the creation of a regulation to tax the cost of medicines marketed in Brazil. First published on 1809, the Regimento dos preços dos medicamentos... gained new editions in the following years and became an indispensable working tool for those involved in the making and trading of drugs at this time. This paper situates historically and sheds light on a document briefly explored by the researchers of the history of the Brazilian pharmacy, taking into account that it was one of the first initiatives of the Luso-Brazilian government in line with the pharmaceutical activity in Brazil in the nineteenth century.

Travestismo y transexualidad en las revistas argentinas de medicina, 1971-1982 / Transvestism and transsexuality in Argentine medical journals, 1971-1982

Resumen El presente artículo aborda los discursos producidos por el campo médico argentino en torno a las iniciativas de corporización de travestis y transexuales en Argentina entre 1971 y 1982. A través del relevamiento y análisis de una selección de artículos publicados en revistas académicas de medicina, se analizan los sentidos que profesionales de la salud asignaron a las mismas antes de la producción de fallos judiciales y normativas nacionales que reconocen la identidad de género como un derecho humano. El análisis realizado permite identificar las particularidades que asumían dichas iniciativas de corporización en el período de estudio, así como las formas en las que el campo médico argentino les imprimió sentidos morales, técnicos y profesionales.

Abstract This article deals with the discourses produced by the Argentine medical field relating to body transformation initiatives on the part of transvestites and transsexuals in Argentina from 1971-1982. Based on the compilation and analysis of a set of articles published in academic medical journals, it examines the meanings that health professionals assigned to these initiatives prior to the legal rulings and national legislation that recognized gender identity as a human right. This analysis helps identify the particular features of those body transformation initiatives during the period studied, as well as the ways in which the medical field in Argentina attached moral, technical and professional meanings to them.

George Deacon and the circulation of homeopathic therapies in Lima (1880-1915) / George Deacon e a circulação de tratamentos homeopáticos em Lima (1880-1915)

Abstract Homeopathy arrived from the United States to Peruvian soil in the last decades of the nineteenth century, broadening the repertoire of existing medical knowledge, which included an emerging medical profession, Chinese herbalists, and indigenous practitioners. This article examines the circulation and use of homeopathic therapies and medicines in Lima from the time when the American homeopath George Deacon initiated his practice, in the 1880s, until his death, in 1915. Although homeopathy was not the most widely used medical therapy in the country, it nevertheless posed a threat to professional medicine and the School of Medicine's desired monopoly of the field of medicine.

Resumo A homeopatia originária dos EUA adentrou solo peruano nas últimas décadas do século XIX, ampliando o repertório de conhecimento médico existente até então, o qual incluía uma profissão médica em ascensão, herbolários chineses e médicos locais. Este artigo analisa a circulação e o uso de tratamentos e medicamentos homeopáticos em Lima desde o período em que o homeopata norte-americano George Deacon iniciou sua prática, nos anos 1880, até sua morte, em 1915. Embora a homeopatia não fosse o tratamento médico mais disseminada no país, ela representou uma ameaça à medicina profissional e ao monopólio do campo da medicina almejado pela escola tradicional.

Breaking the boundaries of professional regulation: medical licensing, foreign influence, and the consolidation of homeopathy in Mexico / Rompendo as barreiras da regulamentação profissional: licenciamento médico, influência estrangeira e consolidação da homeopatia no México

Abstract As doctors sought state support to regulate professional training and practice after Independence, Mexicans also developed different attitudes toward foreign ideas, influences, and professionals. Leveraging the allure of the foreign among Mexicans, homeopaths strategically used work, products, and organizations from abroad to establish their practices and fight changing professional policies in the country that threatened homeopathic institutions. Homeopaths inhabited the blurry and shifting boundary between professional and lay medical practice during the early Republican period, the Porfiriato, and the post-revolutionary era, and used the ambivalent feelings about medical licensing, and foreign influence in Mexican society to consolidate their position.

Resumo Após a independência do país, enquanto os médicos buscavam apoio do Estado para regulamentar o treinamento e a prática profissionais, os mexicanos desenvolveram atitudes diferentes em relação a ideias, influências e profissionais estrangeiros. Aproveitando o encanto dos mexicanos com o estrangeiro, os homeopatas usaram estrategicamente o trabalho, os produtos e as organizações de fora do país para implantar suas práticas e combater as políticas que ameaçavam as instituições ligadas à homeopatia. Os homeopatas ocuparam a barreira nebulosa entre as práticas médicas profissional e leiga no início do período republicano, no Porfiriato e na era pós-revolucionária, usando sentimentos ambivalentes sobre licenciamento médico e influência estrangeira para consolidar sua posição.

Política de saneamento básico no Brasil: discussão de uma trajetória / Basic sanitation policy in Brazil: discussion of a path

Resumo O artigo demonstra que a posição de dominância das empresas estaduais de saneamento condiciona o processo decisório da política pública de saneamento no Brasil. A hegemonia dessas empresas é aqui explicada por meio da análise de uma trajetória que foi capaz de criar incentivos políticos e econômicos que permitiram sua consolidação no tempo. A partir da análise de conteúdo da legislação proposta para o setor e do material produzido pelos grupos de interesse envolvidos na aprovação de um novo marco regulatório setorial em 2007, o trabalho identifica as principais fontes de incentivo instituídas pela adoção do Plano Nacional de Saneamento que explicariam determinados aspectos estruturais na política atual de saneamento e sua forte resiliência às inovações propostas no contexto democrático.

Abstract This article demonstrates that the position of dominance enjoyed by state sanitation companies dictates the public policy decision-making process for sanitation in Brazil. These companies’ hegemony is explained here through the analysis of a path that generated political and economic incentives that have permitted its consolidation over time. Through the content analysis of the legislation proposed for the sector and the material produced by the stakeholders involved in the approval of new regulations for the sector in 2007, the study identifies the main sources of incentive introduced by the adoption of the National Sanitation Plan, which explain certain structural features of the current sanitation policy and its strong capacity to withstand the innovations proposed under democratic rule.

O Hospital Real de Todos-os-Santos e seus agentes da cura / The Hospital Real de Todos-os-Santos and its healing agents

Resumo No final do século XV as instituições de assistência passavam por uma grave crise. Nesse contexto, pretende-se descortinar a ação régia de dom João II (1481-1495), protagonista de uma grande reforma assistencial em Portugal. O rei e sua rainha, dona Leonor, consolidaram um novo modelo assistencial determinando a construção de dois grandes hospitais nos moldes modernos, centralizando a prática assistencial. Por meio de crônicas e de regimentos do período, o artigo focaliza a principal obra hospitalar da época – o Hospital Real de Todos-os-Santos, de Lisboa. A prática dos agentes da saúde também sofre intervenções importantes dos reis de Avis, que regulam, vigiam e fiscalizam a ação de físicos e boticários.

Abstract The article explores the actions of king Dom João II (1481-1495), who spearheaded a major assistance reform in Portugal during the late fifteenth century, when charitable institutions were grappling with a serious crisis. The king and his queen, Dona Leonor, ordered two large, modern hospitals to be built, centralizing assistance work and cementing a new assistance model. Relying on chronicles and royal decrees from the period, the article focuses on the main hospital that was built then: Hospital Real de Todos-os-Santos, located in Lisbon. The king and queen also intervened heavily in the practice of health agents by regulating, overseeing, and inspecting the work of doctors and apothecaries.

Control Discourses and Power Relations of Yellow Fever: Philadelphia in 1793 / 의사학

1793 Yellow fever in Philadelphia was the most severe epidemics in the late 18th century in the United States. More than 10% of the population in the city died and many people fled to other cities. The cause of yellow fever in the United States had close relationship with slaves and sugar in Philadelphia. Sugarcane plantation had needed many labors to produce sugar and lots of Africans had to move to America as slaves. In this process, Aedes aegypti, the vector of yellow fever had migrated to America and the circumstances of ships or cities provided appropriate conditions for its breeding. In this period, the cause of yellow fever could not be established exactly, so suggestions of doctors became entangled in political and intellectual discourses in American society. There was a critical conflict between Jeffersonian Republicanism and Federalism about the origin and treatment of yellow fever. Benjamin Rush, a Jeffersonian Republican, suggested urban sanitation reform and bloodletting. He believed the infectious disease happened because of unsanitary city condition, so he thought the United States could be a healthy nation by improvement of the public health and sanitation. He would like to cope with national crisis and develop American society on the basis of republicanism. While Rush suggested the improvement of public health and sanitation, the city government of Philadelphia suggested isolation of yellow fever patients and quarantine. City government isolated the patients from healthy people and it reconstructed space of hospital. Also, it built orphanages to take care of children who lost their parents during the epidemic and implemented power to control people put in the state of exception. Of course, city government tried to protect the city and nation by quarantine of every ship to Philadelphia. Control policies of yellow fever in 1793 showed different conflicts and interactions. Through the yellow fever, Jeffersonian Republicanism and Federalism had conflicted in politically, but they had interactions for control of the infectious disease. And with these kinds of infectious diseases policies, we can see interactions in local, national and global level.

A Agência Nacional de Vigilância Sanitária e a pesquisa clínica no Brasil / ANVISA and clinical research in Brazil

A realização de ensaios clínicos com medicamentos no Brasil requer aprovação prévia pelos Comitês de Ética em Pesquisa (CEPs) e, em certos casos, pela Comissão Nacional de Ética em Pesquisa (CONEP). Aprovação pela Agência Nacional de Vigilância Sanitária (ANVISA), através de sua Gerência de Medicamentos Novos, Pesquisa e Ensaios Clínicos (GEPEC) é também necessária para ensaios clínicos com medicamentos e produtos para a saúde (correlatos) que são fabricados em outros países e, portanto, necessitam autorização para serem importados. Este artigo revê brevemente a história da legislação sobre pesquisa clínica no Brasil, e apresenta um panorama do papel regulador da ANVISA no presente e suas perspectivas futuras. Pontos importantes discutidos são as legislações novas e futuras da ANVISA, com ênfase nas notificações de eventos adversos e inspeções/auditorias em ensaios clínicos, e seu impacto na pesquisa clínica no Brasil sob o ponto de vista da indústria, da universidade, organizações representativas de pesquisa clínica, médicos e outros profissionais de saúde. A importância para a ANVISA da obtenção de informações a partir de ensaios clínicos para a avaliação do registro de novos medicamentos também é ressaltada.

Modern Medicine Environment and Adaptation of Korean Trader for Medicinal Herbs From the Late 19th Century to the Early 20th Century / 의사학

Since the late 18th century, the Korean traditional medicine trade witnessed a steady growth. There were lots of stores which sold Korean medicinal herbs in Seoul and every major towns had at least one or more stores in Korea, which led to a subsequent growth of people involved in the trade. However, Korean medicine merchants encountered a new environment with the influx of western medicines after the Opening of Ports and the execution of modern medicine policies. Such change of atmosphere led the merchants to seek new breakthroughs. Some of the merchants found the answer in producing and selling patent medicine. The people in the industry had little knowledge of western medicine, so that they had little choice but to combine their experience of Korean medicine with whatever information they had about western counterpart. Such resolution generated a new kind of medicine known as patent medicine. Patent medicine businessmen observed the new medicine policies of the Korean Empire. Some visionary ones even sought to eagerly utilize the trademark system to secure the selling route. The Japanese colonial government strengthened the medicine policies. It revised the legislature and mobilized administrative powers to manage and control the industry. However, such colonial policies in the 1910s implicated certain limits due to its lack of understanding of Korean medicine industry. Also, the colonial government showed poor efforts in introducing modern medicine facilities and systems, so that the ground was set for the patent medicine business to flourish. Patent medicine enjoyed a high turnover. So, the entrepreneurs endeavored to promote the sales in whatever means necessary. The most basic form of advertisement was through the newspaper. Indirect promotion through newspaper articles, issuing medicine flyers, free gift draw, reputation of an influential expert were widely used for its sales. Consequently, patent medicine industry in the 1910s saw a healthy prosperity. One example of such golden days was the case of Hwapyungdangyakbabg(one of the biggest patent medicine companies), which won a third place along with Kyungsungbangjik, which was the top Korean company at that time, in the advertisement design contest hosted by the classified department of Dong-a Daily in 1926. But actually, a few Japanese medicine merchants led the industry. So prosperity of Korean medicine merchant had its limits.